Search results for "Down’s Syndrome"

showing 3 items of 3 documents

Emotional–Behavioral Disorders in Healthy Siblings of Children with Neurodevelopmental Disorders

2020

Background and Objectives: Siblings of disabled children are more at risk of developing mental illnesses. More than 50 international studies show that about 8% of children and adolescents suffer from a mental disorder, which is almost always a source of difficulties both at the interpersonal level (in the family and with peers) and at school. Healthy siblings of children with disabilities are one of the groups most at risk for consequences in psychological health and well-being. As some authors suggest, siblings build their idea of &ldquo

MaleMedicine (General)Coping (psychology)Emotional fragilityAdolescentmedia_common.quotation_subjectautism spectrum disordersEmotional disordereducationfraternal relationshipInterpersonal communicationArticlePsychological health03 medical and health sciencesR5-9200302 clinical medicineDown’s syndromeSDQAdaptation PsychologicalmedicineHumansSibling RelationsPersonality0501 psychology and cognitive sciencesbehavioral disordersSiblingAutism spectrum disorderChildsiblingsmedia_commonbusiness.industry05 social sciencesGeneral Medicineemotional disordermedicine.diseaseSettore MED/39 - Neuropsichiatria Infantileautism spectrum disorders; Down’s syndrome; SDQ; siblings; fraternal relationship; emotional disorder; behavioral disordersNeurodevelopmental DisordersAutism spectrum disorderBehavioral disorderAutism spectrum disorders Behavioral disorders Down’s syndrome Emotional disorder Fraternal relationship SDQ Siblingsbusiness030217 neurology & neurosurgery050104 developmental & child psychologyClinical psychologyMedicina
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Cancer and central nervous system disorders: protocol for an umbrella review of systematic reviews and updated meta-analyses of observational studies

2017

[Background] The objective of this study will be to synthesize the epidemiological evidence and evaluate the validity of the associations between central nervous system disorders and the risk of developing or dying from cancer.

Research designAnorexia NervosaBipolar DisorderMedicine (miscellaneous)lcsh:MedicineDisease0302 clinical medicineDown’s syndromeCentral Nervous System DiseasesNeoplasmsProtocolMedicine030212 general & internal medicineCàncerCancerDepressionIncidenceHuntington’sdiseaseAnorèxia nerviosaAutism spectrum disorders3. Good healthObservational Studies as TopicSystematic reviewResearch DesignMeta-analysisEsquizofrèniaAlzheimer’s diseaseHuntington’s diseasemedicine.medical_specialtyCentral nervous system disorderMultiple SclerosisBipolar disorderSistema nerviós central MalaltiesMEDLINEMultiple sclerosisParkinson’s Disease03 medical and health sciencesMeta-Analysis as TopicDown’s SyndromeHuntington’s DiseaseHumansAlzheimer’s DiseasePsychiatryIntensive care medicineEpilepsybusiness.industrylcsh:RAmyotrophic Lateral SclerosisCancerCentral Nervous System DisorderAnorexia nervosamedicine.diseaseAmyotrophic lateral sclerosisMeta-analysisReview Literature as TopicParkinson’s diseaseSystematic reviewSchizophreniaObservational Studies as TopicObservational studySystematic ReviewAutismebusiness030217 neurology & neurosurgerySystematic Reviews as TopicMeta-Analysis
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Selection of Membrane RNA Aptamers to Amyloid Beta Peptide: Implications for Exosome-Based Antioxidant Strategies

2019

The distribution of amyloid beta peptide 42 (Aβ42) between model exosomal membranes and a buffer solution was measured. The model membranes contained liquid-ordered regions or phosphatidylserine. Results demonstrated that up to ca. 20% of amyloid peptide, generated in the plasma (or intracellular) membrane as a result of proteolytic cleavage of amyloid precursor proteins by β- and γ-secretases, can stay within the membrane milieu. The selection of RNA aptamers that bind to Aβ42 incorporated into phosphatidylserine-containing liposomal membranes was performed using the selection-amplification (SELEX) method. After eight selection cycles, the pool of RNA aptamers was isol…

liposomesphosphatidylserineAmyloidAmyloid betaPeptideexosomesPhosphatidylserinesExosomeCatalysisAntioxidantsraftsInorganic Chemistrylcsh:Chemistrychemistry.chemical_compoundDown’s syndromeoxidative stressHumansRNA aptamersPhysical and Theoretical ChemistryMolecular Biologylcsh:QH301-705.5Spectroscopychemistry.chemical_classificationAmyloid beta-PeptidesbiologyChemistrySELEXCommunicationOrganic ChemistryCell MembraneSELEX Aptamer TechniqueamyloidGeneral MedicinePhosphatidylserineAptamers NucleotideMicrovesiclesPeptide FragmentsComputer Science ApplicationsMembraneBiochemistrylcsh:Biology (General)lcsh:QD1-999biology.proteinAlzheimer’s diseaseSystematic evolution of ligands by exponential enrichmentInternational Journal of Molecular Sciences
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